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Pandas Re-indexing With Multiindex On Index AND Columns

I have a long dataframe with these columns in this format: id gender size region_a_count region_b_count item_group x m x x x x x

Solution 1:

I believe you need set_index with unstack:

df1 = df.set_index(["item_group","size", "id","gender"]).unstack()

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